Ueber einen neuen Formbestandtheil des Säugetierblutes, und die Bedeutung desselben für die Thrombosis und Blutgerinnung überhaupt.

Berlin: Zbl. med. Wiss. 1882, Vorläufige Mitteilung (pp.17-20). , 20/ 2. -August Hirschwald, 14. Januar 1882, 8°, pp.17-32, Fine paper binding..
First Edition in German of Italian publication: "Su di un nuovo elemento morfologico del sanguae dei mammiferi e della sua importanza nella trombosi et nella coagulazione". Osservatore, 1882, 17, 785-87; 18, 97-99.
Giulio Bizzozero "gave the blood platelets their name and found that they play a part in blood coagulation." Item #0000853

Bizzozero (1846-1901) referred in his essay on a new form component of the blood
and its role in thrombosis and coagulation, the platelets, as he called the platelets, as the third independent form component of two to three times smaller diameter than the erythrocytes circulating beside them and the white blood cells in the blood. However, the question of thrombocytogenesis could not really be solved until 1906 by James H. Wright (1869-1928), who observed the formation of platelets from constrictions on the pseudopodia of the megakaryocytes of the bone marrow. A further stimulation of the biostimulatory research by Bizzozero resulted from the fact that he brought the platelets
5in connection with the blood clotting. They, and not the white blood cells, played the main role in the coagulation, because it was likely that the platelets were not only involved in the pathological thrombosis. Bizzozero proposed a bridge to Virchow's view in 1882 with the conclusion that "their proliferation would alter the conditions of the circulation, and it is probable that in such cases the slightest alteration of the walls of the vessel may give rise to widespread thrombosis". Cf. Axel W.Bauer & Kerstin Mall, H- MOSTASE, THROMBOSE AND EMBOLISM. Historical concepts on the physiology and pathology of blood clotting(Garrison & Morton No. 881, Ital.).

Price: $800.00

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